single-cell Data Analysis and VISualization scDAVIS




The possibility of studying the phenotypical and molecular characteristics of the cells in a high-throughput manner is changing our understanding of biological systems. However, the analysis of single-cell omics data requires the use of dimensionality reduction techniques that need to be tailored and correctly interpreted. This fine-tuning is a time-consuming process that requires expert curation to extract the most information out of the data. Also, different high-throughput techniques on the same cell or cellular type are often combined, ranging from cytometry to imaging and transcriptomics.



scDAVIS is a web-based tool for the analysis and visualization of different modalities of single-cell omics data:

(1) scRNA-Seq, (2) Imaging data (Imaris), (3) Cytometry, and (4) General tabular data.




Importantly, scDAVIS is also a repository of publicly a,vailable single-cell experiments, allowing further exploration and reuse of public data, in line with the compliance of FAIR principles. Also, it can serve as a repository to share single-cell data with the community and to ease integration of different datasets.



This version of scDAVIS has the following modules: (1) Load published analysis (currently, 64 public datasets), searchable through a keyword-based search engine. (2) QC-Stats with basic information about cells and features/genes profiled (3) Plots for visualization of results: Dim-Plots, Violin-Plots, Bar-Plots, Heatmaps, Scatter-Plots and Dot-Plots. Finally, scDAVIS incorporates interactive tools for results representation, statistical contrasts, data filtering, and manual annotation/correction.

This tool is created by Carlos Torroja, Daniel Jimenez, Jon Enrique Sicilia, Juan Luis Onieva, Jorge G. García Gómez, Celia Tundidor and Fátima Sanchez-Cabo

Basic info

Number of cells

Number of reads per cells

Number of genes

Distribution of genes

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Distribution of reads

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Public Data

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Plots

Diff Expression Table